Circadian Regulation of Myod 1 Transcription

The goal of the research project is to better understand the role that daily rhythms have in skeletal muscle. These circadian rhythms are important for tissue maintenance and their impairment contributes to obesity and aging. The proposed research is relevant to public health because it is expected to provide new information on how circadian rhythms maintain the daily health of muscle and how their loss may contribute to the decline in muscle function with age and disease.