Clinical Trial of Ceftriaxone in ALS (Supplement): Pilot Study of Lithium in ALS Patients.

The primary study objective is to compare the efficacy of lithium in combination with riluzole to riluzole in combination with placebo in volunteers with ALS. Primary efficacy will be assessed by analyzing disease progression as measured by a 6-point drop in the ALS Functional Rating Scale - Revised (ALSFRS-R) from baseline value or death.