Dual Hit Hypothesis of Aging Related DA Dysfunction

Grants and Contracts Details


We will carryout HPLC-EC studies of postmortem tissues from animal models of Parkinson's disease that are associated with the project from MUSC, directed by Dr. Lotta Granholm. Frozen samples will be sent to UK by FedEx and the samples will be processed for HPLC-EC and analyzed for monoamines and metabolites. The compounds measured will include DA, DOPAC, HVA, NE, 5-HT and 5-HIAA. These studies are being carried out in conjunction with the Morris K. Udall Parkinson's Disease Research of Excellence at UK, which specializes in developing new treatments for Parkinson's disease and determining the pathophysiology of this neurodegenerative disease.
Effective start/end date9/15/056/30/10


  • Medical University of South Carolina: $141,111.00


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