Global CMR Registry Stress perfusion substudy (SPINS trial)

Grants and Contracts Details


Clinical Impact of Stress CMR Perfusion Imaging in the United States (SPINS): A Global CMR Registry Substudy The Global Cardiac Magnetic Resonance Registry (GCMR) registry effort by the Society for Cardiovascular Magnetic Resonance (SMCR) constitutes the only current global effort that includes multiple international CMR programs that span academic, community hospital, and private practice settings ( This is also the only CMR registry that includes a large number of CMR sites in the United States. This proposal aims to assess the clinical impact of stress CMR perfusion guided treatments on patient outcomes in a 2,200 consecutive multicenter patient cohort, referred for assessment of myocardial ischemia in the United States. In the 3 specific aims of the project, we aim to obtain real-world evidence in patient outcomes including mortality and non-fatal cardiac outcomes, downstream cardiac procedures, invasive and non-invasive testing, costs in health care dollars based on national averages, and cardiac event-weighted quality adjusted life years (QALY). We believe these specific aims will provide the core evidence that medical insurance agencies and industries most sought after in making their reimbursement and payment decisions in the United States, towards the use of stress CMR perfusion imaging in patients with chest pain syndromes. Approximately 100 patients are expected to be enrolled at University of Kentucky.
Effective start/end date9/1/173/31/19


  • Society for Cardiovascular Magnetic Resonance: $15,070.00


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