NCI Collaboration

Proposed Concept for Cancer InFocus collaboration between NCI and UK Markey Cancer Center The University of Kentucky Markey Cancer Center (UKMCC) developed Cancer InFocus (CIF) as a suite of tools for gathering and visualizing population health data for cancer surveillance. Code for building the CIF visualization applications is provided to institutions through a no-cost licensing agreement that ensures UKMCC intellectual property rights over CIF, including all derivative products. Institutions are responsible for building and deploying their own institution-specific versions of the Cancer InFocus applications. More information about CIF is available at https://cancerinfocus.org, and examples of existing institution-specific versions can be found at https://cancerinfocus.org/washington/ and https://cancerinfocus.org/philadelphia/. NCI has inquired about the possibility of UKMCC building an institution-specific version of CIF for NCI''s intramural clinical trials office, including the addition of custom features and data streams not currently available in the standard CIF suite of tools. The goal of this expanded NCI-specific version would be to support NCI''s intramural clinical trials office in assessing the reach of their clinical trial accruals and inclusion of special populations of focus. Since institutions are normally required to provide the staff and resources needed to build their own institution-specific CIF versions, NCI would need to compensate UK Markey Cancer Center for staff effort necessary to build an NCI-specific version. Any new product(s) derived from this collaboration would still be considered a derivative product under the Cancer InFocus no-cost licensing agreement, and could be generalized for use by other institutions, including UKMCC. The following is an outline of the proposed NCI-specific version and steps needed to perform the build. The proposed NCI-specific version of CIF will be for internal use at NCI. It will feature the basic CIF components plus additional data and features as needed to meet the needs of PIs at NCI, including additional data from ClinicalTrials.gov and datasets provided by NCI. The product will initially be built to display the immediate catchment area of NCI clinical trials (DC, Maryland and Virginia or “DMV”) and will then be scaled to cover the entire US. The build will encompass at least five aspects, some of which may occur in parallel: 1. Build basic CIF for DMV (time required: 1-2 hours) 2. Add data that NCI provides (time required: 2-4 hours once data is made available) 3. Create data streams that are not currently part of CIF (e.g. ClinicalTrials.gov) and incorporate them into the application (time required: est. 2-3 weeks) 4. Scale from DMV to entire US (time required: 1-2 hours) 5. Training of NCI staff for application maintenance (time required: 1 month) Optional elements could be added that would require additional build time: • New features for CIF application (specifics to be determined) (time required: 1-2 hours per feature) • Creating CIF Profiles application (time required: 2-3 hours) NCI will be responsible for hosting and deploying the application on their own servers. Overall timeframe: est. 2-3 months, contingent upon additional data and features requested and availability of staff from NCI to include in the process.