Ohio Valley Node-Network (OVNN) of the NIDA Clinical Trials Network-CTN 080 (UKRF SOW)

Grants and Contracts Details


STUDY OBJECTIVES. The primary objective of this trial is to evaluate the impact of treating opioid use disorder (OUD) in pregnant women with extended-release (XR) buprenorphine (BUP) compared to sublingual (SL) BUP on mother and infant outcomes. The primary hypotheses are that the BUP-XR, relative to the BUP- SL, group will have significantly: 1) less illicit opioid use during pregnancy; 2) shorter infant hospital length of stay (LOS); and 3) greater postpartum BUP adherence. Testing conceptual models of the mechanisms by which BUP-XR may improve mother-infant outcomes, relative to BUP-SL, is a secondary trial objective.
Effective start/end date6/1/182/29/24


  • University of Cincinnati: $38,077.00


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