Grants and Contracts Details
Description
Intellectual Merit of the Proposed Activity: The axolotl (Ambysloma mexicanum)
collection at Indiana University is a historically significant living resource that is used
actively and widely in biological research. Most notably, axolotls are studied because
they have the ability, unique among vertebrates, to perfectly regenerate numerous parts of
the body, including the brain, spinal cord, fore- and hindlimbs, jaw, and tail, throughout
embryonic, larval, and adult life. The recent and ongoing development of genome
resources for the axolotl and other closely related species is establishing Ambysloma as a
powerful nonmammalian vertebrate model system.
Broader Impacts of the Proposed Activity: The proposal describes a plan to relocate
the IU axolotl collection to the Ambystoma Genetic Stock Center (AGSC) at the
University of Kentucky. Relocation of the collection to the AGSC will consolidate a focal
living stock resource with genome and bioinformatics resources that are currently being
developed for the Ambysloma research community. The AGSC will continue to enable
traditional research areas where the axolotl is the best vertebrate model system (e.g.
regeneration, neoteny). In addition, the AGSC will develop a more inclusive research
provider framework to support a greater diversity ofNSF research and educational
interests.
Status | Finished |
---|---|
Effective start/end date | 7/15/05 → 2/28/10 |
Funding
- National Science Foundation: $990,054.00
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