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Description
Systemic acquired resistance (SAR) is a highly desirable form of resistance that protects
plants against a broad-spectrum of pathogens. During SAR, a mobile signal(s) is generated
at the site of primary infection, which moves systemically to trigger defense in the non-infected
portions of the plant. Current understanding is limited to the knowledge of various molecular
components essential for this mode of defense. Although the phloem is the presumed site of
signal translocation, little has been done to determine the mechanism of intercellular transport
of the SAR inducing signal(s). Potentially, the identification of SAR signal(s) and the knowledge
of their dynamic movement could greatly facilitate the use of SAR in protecting agriculturally
important plants against a wide range of pathogens. This proposal aims to examine the role
of dynamic gating (opening and closing) of the plasmodesmata (PD) in SAR induction and assess
its relationship to some essential mobile SAR inducers. PD gating will be assessed using dye-loading
assays during the time frame of SAR signal generation and movement. Molecular and genetic
tools will be used to alter PD gating within this time frame and assess the effect on SAR.
Metablome analysis of petiole exudates from plants defective in both SAR and PD gating will
be carried out to determine levels of known SAR inducers and to identify other unknown SAR
regulators. Molecular, genetic, and biochemical analyses will be used to characterize the
relationship between PD and various SAR related components.
Status | Finished |
---|---|
Effective start/end date | 8/1/15 → 7/31/21 |
Funding
- National Science Foundation
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Projects
- 1 Finished
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Examining the Importance of Dynamic Trafficking in Systemic Acquired Resistance
Kachroo, A. (PI) & Kachroo, P. (CoI)
8/1/15 → 7/31/23
Project: Research project