PATH Home Trial: Comparative Effectiveness Study of Perpartum Opioid Use Disorder in Rural Kentucky (Georgetown Site Scope)

Grants and Contracts Details


The long term objective of this project is to provide evidence that will fill critical gaps in knowledge regarding the optimal delivery of care to the opioid dependent pregnant women in rural settings. We hope to provide valuable insights regarding approaches to establish evidence-based MAT practice protocols to mitigate the impact of perinatal OUD and, importantly, provide evidence that guides patients and their providers in decisions regarding optimal treatment of perinatal OUD.The specific aims of the study are to: 1) conduct a randomized cluster trial using a ‘hub and spoke’ study design, comparing two active and evidence based elements of our established UK-PATHways program at participating rural regional sites and 2) evaluate the relative effectiveness of each study arm on primary and secondary maternal and neonatal outcomes as compared to the established PATHways program (UK-PATHways: Hub) at the University of Kentucky.
Effective start/end date8/1/1812/31/23


  • Patient-Centered Outcomes Research Institute


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