Grants and Contracts Details
Characterize the extent of fluconazole inhibition of drugs with varying degrees of fraction metabolized (Fm) by CYP2C9 in individuals with the CYP2C9*1/*3 and CYP2C9*3/*3 genotype and apply an enzyme based pharmacokinetic model developed for the CYP2C9 enzyme to determine the change in exposure due to inhibition across drugs with a range of Fm values..
|Effective start/end date||8/15/10 → 1/31/11|
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