Rate of Progression in EYS Related Retinal Degeneration (Pro-EYS)

  • Maldonado, Ramiro (PI)

Grants and Contracts Details


This natural history study of patients with EYS mutations will accelerate the development of outcome measures for clinical trials. Sensitive, reliable outcome measures of retinal degeneration will greatly facilitate development of treatments for retinitis pigmentosa due to EYS mutations. Together these approaches are expected to have an impact on understanding EYS-related retinal degeneration, developing experimental treatment protocols, and assessing their effectiveness. The goals and expected impact of this natural history study are to: 1. Describe the natural history of retinal degeneration in patients with biallelic mutations in the EYS gene 2. Identify sensitive structural and functional outcome measures to use for future multicenter clinical trials in EYS-related retinal degeneration 3. Identify well-defined subpopulations for future clinical trials of investigative treatments for EYS-related retinal degeneration
Effective start/end date4/17/205/9/22


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