Rev1 and Carcinogen-Induced Lung Cancer

  • Wang, Zhigang (PI)

Grants and Contracts Details


The major goal of this project is to generate Rev 1 conditional knockout mice for future studies of lung cancer. The aims are (1) to generate Rev1 conditional knockout mice; and (2) to test the hypothesis that mice deficient in Rev1 are deficient in DNA damage-induced mutagenesis in cultured cells derived from the Rev1-/- transgenic mice (mouse embryonic fibroblasts).
Effective start/end date12/1/1011/30/12


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