Grants and Contracts Details
Description
• Recruit at least two new early career investigators as faculty affiliates. Early career researchers are often eager to gain access to new datasets and establish collaborative (mentor-mentee) relationships. We believe that enthusiastic junior recruits will act as bridges and pull together senior members of NRPA-S’ORCe as generous mentors and willing collaborators.
• Provide biostatistical and bioinformatic support for multiple faculty affiliates. Although we do not envision the NRPA-S’ORCe as a full-blown service center, we see many advantages in having analysts work closely with multiple investigators. This allows analysts to learn new skills, become familiar with new datasets, and develop their own network of collaborators. Equally important, as these analysts become familiar with multiple research programs, they will see first-hand opportunities for synergy among research groups. We believe shared biostatistical and bioinformatic analytical support can be a powerful way to identify new opportunities for collaborative research.
• Streamline data and analytical resources. During the next year, we will streamline data and analytical resources by (1) porting datasets from multiple servers to a common platform, (2) creating an archive of annotated code and instructions for various analytical pipelines, (3) devoting at least one of our monthly meetings to describing and discussing shared data and analytical resources. We believe that streamlining our data and analytical infrastructure will ease the burden of working with these resources, especially for new collaborators."
| Status | Active |
|---|---|
| Effective start/end date | 7/1/23 → … |
Funding
- University of Kentucky Neuroscience Research Priority Area: $20,000.00
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
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Genetic Architecture of Pure Alzheimer's Disease and Mixed Pathology
Fardo, D. (PI) & Katsumata, Y. (CoI)
9/1/23 → 5/31/28
Project: Research project
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Statistical ‘Omics Research Collaborative (S'ORCe)
Fardo, D. (PI), Ebbert, M. T. W. (CoPI), Katsumata, Y. (CoI), Miller, J. (CoI), Zhang, X. (CoI), O'Hara, B. (CoI), Messaoudi Powers, I. (CoI), Nikolajczyk, B. (CoI), Liu, J. (CoI), Jakubek Swartzlander, Y. (CoI) & Steely, C. (CoI)
University of Kentucky Neuroscience Research Priority Area
7/1/22 → …
Project: Research project
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Genetic Architecture of Aging-Related TDP-43 and Mixed Pathology Dementia
Fardo, D. (PI), Ebbert, M. T. W. (CoI), Katsumata, Y. (CoI), Steely, C. (CoI) & Nelson, P. (CoPI)
4/15/23 → 3/31/26
Project: Research project
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Assessing Co-Localization of ITM2B With Alzheimer's Disease and Limbic-Predominant Age-Related TDP-43 Encephalopathy Neuropathologic Changes
Shahidehpour, R. K., Nelson, P. T., Srinivasan, S., Yu, Z. & Bachstetter, A. D., Aug 2025, In: Neuropathology. 45, 4, e70003.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Clonal hematopoiesis of indeterminate potential and the risk of cognitive impairment in the Women's Health Initiative Memory Study
Jakubek, Y. A., Smith, A. P., Leng, X. I., Hall, M. E., Ezzat, D., Pershad, Y., Collins, J. M., Uddin, M. M., Fardo, D. W., Natarajan, P., Bick, A. G., Kitzman, J. O., Honigberg, M. C., Hayden, K. M., Manson, J. A. E., Jaiswal, S., Whitsel, E. A. & Reiner, A. P., Oct 2025, In: Alzheimer's and Dementia. 21, 10, e70737.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Clustering individuals using INMTD: A novel versatile multi-view embedding framework integrating omics and imaging data
Li, Z., Windels, S. F. L., Malod-Dognin, N., Weinberg, S. M., Marazita, M. L., Walsh, S., Shriver, M. D., Fardo, D. W., Claes, P., Przulj, N. & Van Steen, K., Apr 1 2025, In: Bioinformatics. 41, 4, btaf122.Research output: Contribution to journal › Article › peer-review
Open Access