Standard versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury

Abstract copied from clinicaltrials.gov The objectives of this trial are to determine whether, in critically ill patients with severe acute kidney injury (AKI), randomization to accelerated initiation of renal replacement therapy (RRT), compared to standard initiation, leads to: Improved survival (primary outcome); and Recovery of kidney function (principal secondary outcome), defined as independence from RRT at 90 days Study Type: Interventional Study Design: Allocation: Randomized Intervention Model: Parallel Assignment Masking: No masking Primary Purpose: Treatment Official Title: STandard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI): A Multi-Centre, Randomized, Controlled Trial (Principal Trial) Phase : 3