Statins Use in Intracerebral Hemorrhage Patients (SATURN)

  • Pettigrew, Luther (PI)

Grants and Contracts Details

Description

SATURN: Statins Use in Intracerebral Hemorrhage Patients. Primary Objectives: EFFICACY: To determine the effects of continuation vs. discontinuation of statins on the risk of ICH recurrence during 24 months of follow-up in patients presenting with a spontaneous lobar lCH while taking a statin drug. Specifically, we wish to determine the effects of discontinuing vs. continuing statins on the risk of recurrent symptomatic ICH. We hypothesize that discontinuation of statins in patients with lobar ICH is likely associated with reduced risk of ICH recurrence. SAFETY: To determine the effects of discontinuation vs. continuation of statins on the occurrence of any of the following major adverse cardiac and cerebrovascular events (MACCE): symptomatic ischemic stroke, symptomatic myocardial infarction, newly symptomatic arterial occlusive disease (peripheral, retinal, or carotid), revascularization procedures for coronary, carotid, or peripheral arterial disease, and vascular death. We specifically wish to estimate the relative and absolute effects of discontinuing statins on the risk of these MACCE during the 24 month follow-up period. We hypothes
StatusFinished
Effective start/end date4/30/207/26/23

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