The Regulation of Smoothened in Hedgehog Signaling

Grants and Contracts Details


Transfer Proposal - We have proposed the following specific aims in our proposal: 1) To further determine if differential Smo phosphorylation transduces gradient Hh activity; 2) to investigate the molecular mechanisms by which G protein-coupled receptor kinase 2 (GRK2) is involved in Hh signaling; and 3) to determine the role of phosphatase in Smo dephosphorylation and inactivation.
Effective start/end date7/1/096/30/14


  • National Institute of General Medical Sciences: $1,214,236.00


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