Projects and Grants per year
Grants and Contracts Details
Description
The University of Kentucky Cancer Nanotechnology Training Center (UK CNTC) will provide advanced
multidisciplinary training for predoctoral students and postdoctoral fellows toward the goal of creating a new
type of cancer researcher who is skilled and ready to pursue a career in cancer nanotechnology research.
Nationally and internationally recognized faculty members at the University of Kentucky will collaborate to
create a fertile environment for the novel exploration of nanotechnology and cancer. Expertise covers a broad
multidisciplinary range of scientific areas in gastrointestinal cancer, lung cancer, gliomas, radiation medicine,
surgery, cancer screening, imaging, and pharmacokinetics and dynamics. Among these faculty are 16
nanotechnology researchers in the Departments of Chemical Engineering, Materials Engineering, Electrical
Engineering, Chemistry, and Pharmaceutical Sciences and 18 biomedical scientists or clinical oncologists in
the Colleges of Pharmacy or Medicine. Based on existing research collaborations, we propose cancer
nanotechnology projects composed of multidisciplinary focus area teams with the goal of training future leading
researchers in the field of cancer nanotechnology in the following four areas: (1) early detection and diagnosis
in lung, colon, and ovarian cancer; (2) treatment of gastrointestinal tumors and metastases; (3) lung cancer
treatment; and (4) glioma therapy. Specific Aim 1 is to expand the core expertise of participants in the UK
CNTC through cross-disciplinary laboratory research training projects of up to two years involving innovative
applications of nanotechnology to address specific unmet needs in cancer detection and therapy. Our trainees
will be at the forefront of research that will be driven toward developing novel cancer therapies and diagnostic
strategies based on nanotechnology. Through these activities, the trainees will obtain a detailed understanding
of the molecular basis of cancer, the unresolved clinical problems in treating and diagnosing the disease, and
acquire expertise in the field of nanotechnology. In Specific Aim 2, the CNTC will provide trainees with
problem-based and experiential training through seminars, workshops, short courses, clerkships, and
laboratory training modules that will build their research skills and confidence as members of multi-disciplinary
research teams. Each trainee will be immersed in individualized problem-based instruction and a broad
multidisciplinary training through core courses, short courses, participation in seminars, undergraduate and
early graduate student mentoring, and outreach activities designed to educate the public. Trainees will be
guided through these programs with effective mentorship and an evaluation program (Specific Aim 3) that will
assess the effectiveness of trainee progress and development. Finally, Specific Aim 4 is to highlight the
accomplishments of CNTC trainees both regionally and nationally. As such, our trainees will learn to envision,
articulate, and perform nanotechnology-centered research focused on developing novel solutions to the
outstanding clinical problems associated with cancer.
Status | Finished |
---|---|
Effective start/end date | 9/3/10 → 7/31/14 |
Funding
- National Cancer Institute: $442,640.00
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Projects
- 1 Finished
-
SCOPE: Carry-Forward--The University of Kentucky Cancer Nanotechnology Training Center (UK CNTC)
Anderson, B. (PI), Anderson, K. (CoI), Evers, B. M. (CoI), Hilt, J. (CoI), Moscow, J. (CoI) & Yokel, R. (CoI)
9/3/10 → 7/31/14
Project: Research project