Transcription Factor Isoform-specific Regulation of Hormone Gene Expression

~a~y transcription factors a~eexpressed as mul~ipleisoforms defined by conserved structural Imtifs yet with dlstm':1effects on.the regulation.of gene expressIOn,tumorigenesis and the specificity of molecular cancer !heraples. AnalysIs of the funct.lOnalconsequences of structural differences between transcription factor Isoforms may allow more specific control of gene expression, and more effective anti-cancer therapies. The transcriptio~ fact