Grants and Contracts Details
Description
Lung cancer remains the most common cause of cancer deaths in the United States. Although clinical
trials are recognized as critical to therapeutic progress, the patient participation rate remains very low.
One major impediment to clinical trial participation is the time and effort required to identify patients who
fit the eligibility requirements of specific studies at the point of care in a busy clinical context. Typically,
patient identification requires that the treating oncologist a) thinks about clinical trials as an option; b)
identifies clinical trials that may be appropriate for their patient; and c) compares their patient’s clinical
and laboratory features against specific eligibility criteria of available studies. This project will address
this practical barrier to clinical trial accrual through development of Trial Prospector, an automated
clinical trial matching program. Trial Prospector retrieves clinical information from hospital electronic
systems, and matches this information to eligibility criteria in a clinical trials database. The Trial
Prospector prototype was feasible to implement in a cancer treatment center, and oncologists found it
to be useful. This project has 2 Specific Aims: 1) To integrate lung cancer-specific enhancements (e.g.
molecular characteristics) and other general enhancements into the current Trial Prospector prototype,
and 2) To evaluate the accuracy, usability and accrual impact of Trial Prospector as a point-of-care tool
in Thoracic Oncology outpatient clinics at the Seidman Cancer Center of the Case Comprehensive
Cancer Center. The overall goal is to accelerate progress against lung cancer by removing a major
practical barrier to clinical trial accrual.
Status | Finished |
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Effective start/end date | 2/15/16 → 2/14/18 |
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