Crystals of the title compound, C26H31NO3, were obtained by the reaction of 1-naphthyl-methyl-amine with parthenolide. X-ray crystal structure determination reveals a stacked conformation between the cyclo-decane ring of the parthenol-ide moiety and the pendant naphthalene ring. The configuration of the new chiral center at C11 (the point of attachment of the naphthyl-methyl-amino side group) in the title compound is R, establishing the stereospecificity of the amination reaction.
|Journal||Acta Crystallographica Section E: Structure Reports Online|
|State||Published - Oct 5 2007|
ASJC Scopus subject areas
- Chemistry (all)
- Materials Science (all)
- Condensed Matter Physics