Abstract
Background: 20-Hydroxyecdysone (20E) and juvenile hormone (JH) coordinately control insect molting and metamorphosis. Results: Induced by 20E and suppressed by JH, E93 acts through GAGA-containing motifs and up-regulates a subset of 20E response genes. Conclusion: E93 transcriptionally modulates 20E signaling to promote Bombyx metamorphosis. Significance: Our study helps in understanding the complicated molecular mechanisms of insect metamorphosis.
| Original language | English |
|---|---|
| Pages (from-to) | 27370-27383 |
| Number of pages | 14 |
| Journal | Journal of Biological Chemistry |
| Volume | 290 |
| Issue number | 45 |
| DOIs | |
| State | Published - Nov 6 2015 |
Bibliographical note
Publisher Copyright:© 2015 by The American Society for Biochemistry and Molecular Biology, Inc.
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Cell Biology
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