A 35 kDa Fos-related antigen is co-localized with substance P and dynorphin in striatal neurons

W. Q. Zhang; K. R. Pennypacker; H. Ye; I. J. Merchenthaler; L. Grimes; M. J. Iadarola; J. S. Hong

doi:10.1016/0006-8993(92)90289-L

A 35 kDa Fos-related antigen is co-localized with substance P and dynorphin in striatal neurons

W. Q. Zhang, K. R. Pennypacker, H. Ye, I. J. Merchenthaler, L. Grimes, M. J. Iadarola, J. S. Hong

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

The rat striatum after dopamine denervation followed by repeated apomorphine treatment was examined for the co-expression of c-fos and Fos-related antigens with dynorphin, substance P and [Met⁵]enkephalin using Western blot and immunohistochemical techniques. Administration of apomorphine, a dopamine agonist, elevated the level of 35 kDa Fos-related antigen which co-localized with dynorphin and substance P, but not enkephalin, in striatal neurons.

Original language	English
Pages (from-to)	312-317
Number of pages	6
Journal	Brain Research
Volume	577
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(92)90289-L
State	Published - Apr 17 1992

Keywords

6-Hydroxydopamine
Apomorphine
Dynorphin
Enkephalin
Striatum
Substance P

ASJC Scopus subject areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(92)90289-L

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title = "A 35 kDa Fos-related antigen is co-localized with substance P and dynorphin in striatal neurons",

abstract = "The rat striatum after dopamine denervation followed by repeated apomorphine treatment was examined for the co-expression of c-fos and Fos-related antigens with dynorphin, substance P and [Met5]enkephalin using Western blot and immunohistochemical techniques. Administration of apomorphine, a dopamine agonist, elevated the level of 35 kDa Fos-related antigen which co-localized with dynorphin and substance P, but not enkephalin, in striatal neurons.",

keywords = "6-Hydroxydopamine, Apomorphine, Dynorphin, Enkephalin, Striatum, Substance P",

author = "Zhang, {W. Q.} and Pennypacker, {K. R.} and H. Ye and Merchenthaler, {I. J.} and L. Grimes and Iadarola, {M. J.} and Hong, {J. S.}",

year = "1992",

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doi = "10.1016/0006-8993(92)90289-L",

language = "English",

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pages = "312--317",

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TY - JOUR

T1 - A 35 kDa Fos-related antigen is co-localized with substance P and dynorphin in striatal neurons

AU - Zhang, W. Q.

AU - Pennypacker, K. R.

AU - Ye, H.

AU - Merchenthaler, I. J.

AU - Grimes, L.

AU - Iadarola, M. J.

AU - Hong, J. S.

PY - 1992/4/17

Y1 - 1992/4/17

N2 - The rat striatum after dopamine denervation followed by repeated apomorphine treatment was examined for the co-expression of c-fos and Fos-related antigens with dynorphin, substance P and [Met5]enkephalin using Western blot and immunohistochemical techniques. Administration of apomorphine, a dopamine agonist, elevated the level of 35 kDa Fos-related antigen which co-localized with dynorphin and substance P, but not enkephalin, in striatal neurons.

AB - The rat striatum after dopamine denervation followed by repeated apomorphine treatment was examined for the co-expression of c-fos and Fos-related antigens with dynorphin, substance P and [Met5]enkephalin using Western blot and immunohistochemical techniques. Administration of apomorphine, a dopamine agonist, elevated the level of 35 kDa Fos-related antigen which co-localized with dynorphin and substance P, but not enkephalin, in striatal neurons.

KW - 6-Hydroxydopamine

KW - Apomorphine

KW - Dynorphin

KW - Enkephalin

KW - Striatum

KW - Substance P

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DO - 10.1016/0006-8993(92)90289-L

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AN - SCOPUS:0026604197

SN - 0006-8993

VL - 577

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JO - Brain Research

JF - Brain Research

IS - 2

ER -

A 35 kDa Fos-related antigen is co-localized with substance P and dynorphin in striatal neurons

Abstract

Keywords

ASJC Scopus subject areas

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