A 35 kDa Fos-related antigen is co-localized with substance P and dynorphin in striatal neurons

W. Q. Zhang, K. R. Pennypacker, H. Ye, I. J. Merchenthaler, L. Grimes, M. J. Iadarola, J. S. Hong

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

The rat striatum after dopamine denervation followed by repeated apomorphine treatment was examined for the co-expression of c-fos and Fos-related antigens with dynorphin, substance P and [Met5]enkephalin using Western blot and immunohistochemical techniques. Administration of apomorphine, a dopamine agonist, elevated the level of 35 kDa Fos-related antigen which co-localized with dynorphin and substance P, but not enkephalin, in striatal neurons.

Original languageEnglish
Pages (from-to)312-317
Number of pages6
JournalBrain Research
Volume577
Issue number2
DOIs
StatePublished - Apr 17 1992

Keywords

  • 6-Hydroxydopamine
  • Apomorphine
  • Dynorphin
  • Enkephalin
  • Striatum
  • Substance P

ASJC Scopus subject areas

  • Neuroscience (all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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