Abstract
Human behavioral pharmacology methods have been used to rigorously evaluate the effects of a range of centrally acting drugs in humans under controlled conditions for decades. Methods like drug self-administration and drug discrimination have been adapted from nonhuman laboratory animal models. Because humans have the capacity to communicate verbally, self-report methods are also commonly used to understand drug effects. This perspective article provides an overview of these traditional human behavioral pharmacology methods and introduces some novel methodologies that have more recently been adapted for use in the field. Design (e.g., using placebo controls, testing multiple doses) and ethical (e.g., avoiding enrollment of individuals seeking treatment, determining capacity to consent) considerations that must be addressed when conducting these types of studies are also described.
Original language | English |
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Pages (from-to) | 361-381 |
Number of pages | 21 |
Journal | Perspectives on Behavior Science |
Volume | 45 |
Issue number | 2 |
DOIs | |
State | Published - Jun 2022 |
Bibliographical note
Publisher Copyright:© 2022, Association for Behavior Analysis International.
Keywords
- Behavior
- Discriminative stimulus effects
- Human
- Pharmacology
- Reinforcing effects
- Subjective effects
ASJC Scopus subject areas
- Social Psychology
- Experimental and Cognitive Psychology
- Clinical Psychology