Abstract
A Campylobacter jejuni homolog of the lcrD/flbF family of genes was cloned and sequenced. The nucleotide sequence of the gene, called flbA, predicted a protein of 78,864 Da, with significant homology to a group of related proteins including the Yersinia pestis LcrD, Salmonella typhimurium InvA, and Caulobacter crescentus FlbF proteins. The greatest homology was seen with the C. crescentus FlbF protein, with an overall amino acid sequence homology of 57%. An insertion mutation in the C. jejuni 81-176 flbA gene was constructed. The resultant strain did not synthesize flagellin and was nonmotile.
| Original language | English |
|---|---|
| Pages (from-to) | 2930-2936 |
| Number of pages | 7 |
| Journal | Infection and Immunity |
| Volume | 61 |
| Issue number | 7 |
| State | Published - 1993 |
Funding
| Funders | Funder number |
|---|---|
| National Institute of Allergy and Infectious Diseases | R29AI027908 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
ASJC Scopus subject areas
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases
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