A case of rapidly progressing lung spindle cell carcinoma presenting as Pancoast syndrome

Naoki Misumida; Ryo Sanda; Akiko Ota; Motoaki Kato; Yasuyuki Takagi; Ayako Yagi; Yasuteru Sugino; Michiko Fujii; Yushi Saitou

A case of rapidly progressing lung spindle cell carcinoma presenting as Pancoast syndrome

Naoki Misumida, Ryo Sanda, Akiko Ota, Motoaki Kato, Yasuyuki Takagi, Ayako Yagi, Yasuteru Sugino, Michiko Fujii, Yushi Saitou

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

We report a case of rapidly progressing spindle cell carcinoma presenting as Pancoast syndrome. The patient was a 59-year-old woman with a chief complaint of right forearm paresthesia. A chest computed tomography revealed a huge tumor in S1 and S2 in the right lung, invading the upper mediastinum and the first rib. A CT-guided lung biopsy was performed. H-E stain of the tissue revealed spindle-shaped tumor cells proliferating diffusely in a streaming pattern without definitive squamous or glandular differentiation. Immunohistochemical stains with CAM 5.2 and vimentin were positive for tumor cells. Based on a pathological diagnosis of spindle cell carcinoma (cT4N3M1, stage IV) she was treated with chemoradiotherapy. Despite treatment, the patient died 6 months after presenting.

Original language	English
Pages (from-to)	865-869
Number of pages	5
Journal	Nihon Kyobu Shikkan Gakkai zasshi
Volume	47
Issue number	10
State	Published - Oct 2009

ASJC Scopus subject areas

General Medicine

Cite this

@article{988e8c7cd458485097241b5a27002b8b,

title = "A case of rapidly progressing lung spindle cell carcinoma presenting as Pancoast syndrome",

abstract = "We report a case of rapidly progressing spindle cell carcinoma presenting as Pancoast syndrome. The patient was a 59-year-old woman with a chief complaint of right forearm paresthesia. A chest computed tomography revealed a huge tumor in S1 and S2 in the right lung, invading the upper mediastinum and the first rib. A CT-guided lung biopsy was performed. H-E stain of the tissue revealed spindle-shaped tumor cells proliferating diffusely in a streaming pattern without definitive squamous or glandular differentiation. Immunohistochemical stains with CAM 5.2 and vimentin were positive for tumor cells. Based on a pathological diagnosis of spindle cell carcinoma (cT4N3M1, stage IV) she was treated with chemoradiotherapy. Despite treatment, the patient died 6 months after presenting.",

author = "Naoki Misumida and Ryo Sanda and Akiko Ota and Motoaki Kato and Yasuyuki Takagi and Ayako Yagi and Yasuteru Sugino and Michiko Fujii and Yushi Saitou",

year = "2009",

month = oct,

language = "English",

volume = "47",

pages = "865--869",

journal = "Nihon Kyobu Shikkan Gakkai zasshi",

issn = "1343-3490",

publisher = "Elsevier BV",

number = "10",

}

TY - JOUR

T1 - A case of rapidly progressing lung spindle cell carcinoma presenting as Pancoast syndrome

AU - Misumida, Naoki

AU - Sanda, Ryo

AU - Ota, Akiko

AU - Kato, Motoaki

AU - Takagi, Yasuyuki

AU - Yagi, Ayako

AU - Sugino, Yasuteru

AU - Fujii, Michiko

AU - Saitou, Yushi

PY - 2009/10

Y1 - 2009/10

N2 - We report a case of rapidly progressing spindle cell carcinoma presenting as Pancoast syndrome. The patient was a 59-year-old woman with a chief complaint of right forearm paresthesia. A chest computed tomography revealed a huge tumor in S1 and S2 in the right lung, invading the upper mediastinum and the first rib. A CT-guided lung biopsy was performed. H-E stain of the tissue revealed spindle-shaped tumor cells proliferating diffusely in a streaming pattern without definitive squamous or glandular differentiation. Immunohistochemical stains with CAM 5.2 and vimentin were positive for tumor cells. Based on a pathological diagnosis of spindle cell carcinoma (cT4N3M1, stage IV) she was treated with chemoradiotherapy. Despite treatment, the patient died 6 months after presenting.

AB - We report a case of rapidly progressing spindle cell carcinoma presenting as Pancoast syndrome. The patient was a 59-year-old woman with a chief complaint of right forearm paresthesia. A chest computed tomography revealed a huge tumor in S1 and S2 in the right lung, invading the upper mediastinum and the first rib. A CT-guided lung biopsy was performed. H-E stain of the tissue revealed spindle-shaped tumor cells proliferating diffusely in a streaming pattern without definitive squamous or glandular differentiation. Immunohistochemical stains with CAM 5.2 and vimentin were positive for tumor cells. Based on a pathological diagnosis of spindle cell carcinoma (cT4N3M1, stage IV) she was treated with chemoradiotherapy. Despite treatment, the patient died 6 months after presenting.

UR - https://www.scopus.com/pages/publications/73349120275

UR - https://www.scopus.com/inward/citedby.url?scp=73349120275&partnerID=8YFLogxK

M3 - Review article

C2 - 19882907

AN - SCOPUS:73349120275

SN - 1343-3490

VL - 47

SP - 865

EP - 869

JO - Nihon Kyobu Shikkan Gakkai zasshi

JF - Nihon Kyobu Shikkan Gakkai zasshi

IS - 10

ER -

A case of rapidly progressing lung spindle cell carcinoma presenting as Pancoast syndrome

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this