Abstract
There is an increasing recognition that atherosclerotic lesion composition, rather than size, is the determinant of acute events. Immunostaining is a commonly used method to characterize atherosclerotic lesion compositions. Here, we describe a color segmentation-based approach in HSI (hue, saturation, and intensity) color mode, which minimizes subjectivity and produces accurate and consistent quantifications of atherosclerotic lesion compositions.
Original language | English |
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Title of host publication | Methods in Molecular Biology |
Pages | 21-30 |
Number of pages | 10 |
DOIs | |
State | Published - 2017 |
Publication series
Name | Methods in Molecular Biology |
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Volume | 1614 |
ISSN (Print) | 1064-3745 |
Bibliographical note
Publisher Copyright:© 2017, Springer Science+Business Media LLC.
Keywords
- Antibody
- Atherosclerosis
- Color
- Imaging
- Immunostaining
ASJC Scopus subject areas
- Molecular Biology
- Genetics