TY - JOUR
T1 - A concise synthesis of (S)-(+)-1-(4-{2-[bis-(4-fluorophenyl)methoxy]-ethyl} piperazin-1-yl)-2-phenylpropan-2-ol dimaleate
AU - Prisinzano, Thomas
AU - Hsin, Ling Wei
AU - Folk, John E.
AU - Flippen-Anderson, Judith L.
AU - George, Clifford
AU - Jacobson, Arthur E.
AU - Rice, Kenner C.
N1 - Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2003/10/31
Y1 - 2003/10/31
N2 - (S)-(+)-1-(4-{2-[Bis-(4-fluorophenyl)methoxy]-ethyl}piperazin-1-yl) -2-phenylpropan-2-ol dimaleate was prepared in several steps from (S)-(+)-atrolactic acid by a process permitting synthesis of multigram quantities. With the information provided by asymmetric synthesis, the X-ray crystal structure was solved.
AB - (S)-(+)-1-(4-{2-[Bis-(4-fluorophenyl)methoxy]-ethyl}piperazin-1-yl) -2-phenylpropan-2-ol dimaleate was prepared in several steps from (S)-(+)-atrolactic acid by a process permitting synthesis of multigram quantities. With the information provided by asymmetric synthesis, the X-ray crystal structure was solved.
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U2 - 10.1016/j.tetasy.2003.05.001
DO - 10.1016/j.tetasy.2003.05.001
M3 - Article
AN - SCOPUS:0142258185
SN - 0957-4166
VL - 14
SP - 3285
EP - 3289
JO - Tetrahedron Asymmetry
JF - Tetrahedron Asymmetry
IS - 21
ER -