TY - JOUR
T1 - A Facile One-Pot Synthesis of Symmetrical and Unsymmetrical Acetaldehyde Acetals from Primary Alcohols
AU - Guy, Rodney Kiplin
AU - DiPietro, Richard Anthony
PY - 1992/3/1
Y1 - 1992/3/1
N2 - Initial formation of a vinyl ether 2 by treatment of a primary alcohol 1 with ethyl vinyl ether in the presence of mercury (II) acetate followed by treatment with the same or a different alcohol in the presence of p-toluenesulfonic acid affords the symmetrical and unsymmetrical acetaldehyde acetals 3 in good overall yield. The method is easily scaled up and represents a significant improvement over currently available procedures.
AB - Initial formation of a vinyl ether 2 by treatment of a primary alcohol 1 with ethyl vinyl ether in the presence of mercury (II) acetate followed by treatment with the same or a different alcohol in the presence of p-toluenesulfonic acid affords the symmetrical and unsymmetrical acetaldehyde acetals 3 in good overall yield. The method is easily scaled up and represents a significant improvement over currently available procedures.
UR - http://www.scopus.com/inward/record.url?scp=0026513681&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026513681&partnerID=8YFLogxK
U2 - 10.1080/00397919208019270
DO - 10.1080/00397919208019270
M3 - Article
AN - SCOPUS:0026513681
SN - 0039-7911
VL - 22
SP - 687
EP - 692
JO - Synthetic Communications
JF - Synthetic Communications
IS - 5
ER -