A Facile One-Pot Synthesis of Symmetrical and Unsymmetrical Acetaldehyde Acetals from Primary Alcohols

Rodney Kiplin Guy, Richard Anthony DiPietro

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Initial formation of a vinyl ether 2 by treatment of a primary alcohol 1 with ethyl vinyl ether in the presence of mercury (II) acetate followed by treatment with the same or a different alcohol in the presence of p-toluenesulfonic acid affords the symmetrical and unsymmetrical acetaldehyde acetals 3 in good overall yield. The method is easily scaled up and represents a significant improvement over currently available procedures.

Original languageEnglish
Pages (from-to)687-692
Number of pages6
JournalSynthetic Communications
Volume22
Issue number5
DOIs
StatePublished - Mar 1 1992

ASJC Scopus subject areas

  • Organic Chemistry

Fingerprint

Dive into the research topics of 'A Facile One-Pot Synthesis of Symmetrical and Unsymmetrical Acetaldehyde Acetals from Primary Alcohols'. Together they form a unique fingerprint.

Cite this