A general psychopathology factor (P Factor) in children: Structural model analysis and external validation through familial risk and child global executive function

Michelle M. Martel, Pedro M. Pan, Maurício S. Hoffmann, Ary Gadelha, Maria C. do Rosário, Jair J. Mari, Gisele G. Manfro, Eurípedes C. Miguel, Tomás Paus, Rodrigo A. Bressan, Luis A. Rohde, Giovanni A. Salum

Research output: Contribution to journalArticlepeer-review

130 Scopus citations

Abstract

High rates of comorbidities and poor validity of disorder diagnostic criteria for mental disorders hamper advances in mental health research. Recent work has suggested the utility of continuous cross-cutting dimensions, including general psychopathology and specific factors of externalizing and internalizing (e.g., distress and fear) syndromes. The current study evaluated the reliability of competing structural models of psychopathology and examined external validity of the best fitting model on the basis of family risk and child global executive function (EF). A community sample of 8,012 families from Brazil with children ages 6-12 years completed structured interviews about the child and parental psychiatric syndromes, and a subsample of 2,395 children completed tasks assessing EF (i.e., working memory, inhibitory control, and time processing). Confirmatory factor analyses tested a series of structural models of psychopathology in both parents and children. The model with a general psychopathology factor ("P factor") with 3 specific factors (fear, distress, and externalizing) exhibited the best fit. The general P factor accounted for most of the variance in all models, with little residual variance explained by each of the 3 specific factors. In addition, associations between child and parental factors were mainly significant for the P factors and nonsignificant for the specific factors from the respective models. Likewise, the child P factor-but not the specific factors-was significantly associated with global child EF. Overall, our results provide support for a latent overarching P factor characterizing child psychopathology, supported by familial associations and child EF.

Original languageEnglish
Pages (from-to)137-148
Number of pages12
JournalJournal of Abnormal Psychology
Volume126
Issue number1
DOIs
StatePublished - Jan 1 2017

Keywords

  • Children
  • Executive function
  • Familial risk
  • P factor
  • Structural model

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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