A lewis acid-catalyzed procedure for the conversion of 2-methoxyethoxymethyl ethers to carboxylic esters

Raymond S. Gross, David S. Watt

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

A procedure for the conversion of 2-methoxyethoxymethyl (MEM) ethers to carboxylic esters employed ferric chloride (0.4 equivalents) and a carboxylic anhydride (14 equivalents) and exhibited selectivity for the MEM ether functionality in the presence of benzyl ethers.

Original languageEnglish
Pages (from-to)1749-1760
Number of pages12
JournalSynthetic Communications
Volume17
Issue number15
DOIs
StatePublished - Nov 1 1987

Bibliographical note

Funding Information:
We thank the National Institutes of Health (GM 36256) for their generous financial support and the University of Kentucky Mass Spectrometry Center and the

ASJC Scopus subject areas

  • Organic Chemistry

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