A matter of life or death (or both): Understanding autophagy in cancer

William N. Hait, Shengkan Jin, Jin Ming Yang

Research output: Contribution to journalReview articlepeer-review

70 Scopus citations


Autophagy is a highly conserved pathway that can be used for survival during nutrient and growth factor deprivation. Under certain circumstances, it seems that autophagy may serve as a pathway to cell death. Already, it is becoming increasingly clear that autophagy is involved in cancer formation, survival, and response to several forms of cancer treatments. A detailed understanding of how this pathway is regulated is now emerging and will allow translation of this information into new approaches to cancer treatment.

Original languageEnglish
Pages (from-to)1961-1965
Number of pages5
JournalClinical Cancer Research
Issue number7 I
StatePublished - Apr 1 2006

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'A matter of life or death (or both): Understanding autophagy in cancer'. Together they form a unique fingerprint.

Cite this