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A model of the pacemaking neuron of the respiratory central pattern generator

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We have developed a model of the mammalian respiratory central pattern generator (rCPG) to mimic the salient characteristics of its constituent medullary neurons. This model is designed as a network of Hodgkin-Huxley-type medullary neurons driven by a pacemaking neuron from the pre-Bötzinger complex. Here, we present the results of our model of this pacemaking neuron, based on available voltage clamp data. Implications for the behavior of the rCPG are discussed.

Original languageEnglish
Pages (from-to)120-124
Number of pages5
JournalIEEE Transactions on Neural Systems and Rehabilitation Engineering
Volume13
Issue number2
DOIs
StatePublished - Jun 2005

Funding

FundersFunder number
U.S. National Library of MedicineT15LM007093

    Keywords

    • Biological system modeling
    • Hodgkin-Huxley models
    • Neural networks
    • Respiratory system

    ASJC Scopus subject areas

    • Internal Medicine
    • General Neuroscience
    • Biomedical Engineering
    • Rehabilitation

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