A morphology index based on sonographic findings in ovarian cancer

P. D. De Priest, D. Shenson, A. Fried, J. E. Hunter, S. J. Andrews, H. H. Gallion, E. J. Pavlik, R. J. Kryscio, J. R. Van Nagell

Research output: Contribution to journalArticlepeer-review

210 Scopus citations

Abstract

A morphology index based on morphologic characteristics of ovarian tumors was developed. Specific categories included tumor volume, wall structure, and septal structure. A point scale (0-4) was developed within each category with the total points per evaluation varying from 0-12. Sonograms on 121 patients undergoing exploratory laparotomy for ovarian masses were evaluated using this index. Eighty ovarian tumors had a morphology index score <5, and all were benign (negative predictive value, 1.000). In postmenopausal patients, a morphology index score ≥5 had a positive predictive value for malignancy of 0.45. All ovarian malignancies had significant abnormalities in wall structure and all had a total volume in excess of 10 cm3. The findings of the present investigation indicate that the morphology index is a cost effective adjuvant method which significantly increases the specificity and positive predictive value of transvaginal sonography. The routine application of a morphology index to screening sonography should decrease the amount of diagnostic surgery performed in order to detect each case of ovarian cancer.

Original languageEnglish
Pages (from-to)7-11
Number of pages5
JournalGynecologic Oncology
Volume51
Issue number1
DOIs
StatePublished - Oct 1993

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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