Abstract
Ru(bpy)2dppz, a well studied “light-switch” metal complex, transforms into a photochemical “light-switch” and DNA damaging agent by incorporating structural strain. This distorted compound is photoreactive and ejects a ligand upon binding duplex and G-quadruplex DNA, producing a reactive metal center that metalates the DNA.
Original language | English |
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Pages (from-to) | 311-313 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 50 |
Issue number | 3 |
DOIs | |
State | Published - Dec 3 2014 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- General Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry