A partial synthesis of picrasin B and Δ2-picrasin B

Kenji Kawada, Moonsun Kim, David S. Watt

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


The regioselective reductive demethylation of the O-methyldiosphenol functionality in the A ring of quassin (3) with chlorotrimethylsilane and sodium iodide furnished picrasin B (1). Swern oxidation of 1 furnished Δ2-picrasin B (2), and O-methylation of 2 regenerated quassin (3).

Original languageEnglish
Pages (from-to)5985-5988
Number of pages4
JournalTetrahedron Letters
Issue number44
StatePublished - 1989

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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