TY - JOUR
T1 - A Perspective on Emerging Therapeutic Interventions for COVID-19
AU - Torequl Islam, Muhammad
AU - Nasiruddin, Md
AU - Khan, Ishaq N.
AU - Mishra, Siddhartha Kumar
AU - Kudrat-E-Zahan, Md
AU - Alam Riaz, Thoufiqul
AU - Ali, Eunus S.
AU - Rahman, M. Safiur
AU - Mubarak, Mohammad S.
AU - Martorell, Miquel
AU - Cho, William C.
AU - Calina, Daniela
AU - Docea, Anca Oana
AU - Sharifi-Rad, Javad
N1 - Publisher Copyright:
© Copyright © 2020 Torequl Islam, Nasiruddin, Khan, Mishra, Kudrat-E-Zahan, Alam Riaz, Ali, Rahman, Mubarak, Martorell, Cho, Calina, Docea and Sharifi-Rad.
PY - 2020/7/3
Y1 - 2020/7/3
N2 - Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed.
AB - Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed.
KW - COVID-19 pandemic
KW - SARS-CoV-2
KW - control
KW - public health
KW - therapeutics
UR - http://www.scopus.com/inward/record.url?scp=85088438912&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85088438912&partnerID=8YFLogxK
U2 - 10.3389/fpubh.2020.00281
DO - 10.3389/fpubh.2020.00281
M3 - Review article
AN - SCOPUS:85088438912
VL - 8
JO - Frontiers in Public Health
JF - Frontiers in Public Health
M1 - 281
ER -
