A single-step polymerization method for poly(β-amino ester) biodegradable hydrogels

Dipti Biswal, Paritosh P. Wattamwar, Thomas D. Dziubla, J. Zach Hilt

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


A novel one-step method for the preparation of poly(β-amino ester) hydrogels has been developed. The one-step method utilizes a Michael type addition reaction between a difunctional diacrylate and a tetrafunctional primary diamine to create a crosslinked biodegradable hydrogel. It was shown that the molar ratio of the reactive acrylate to amine controlled the extent of polymerization and crosslinking density of the hydrogel system, which enabled for the end properties of the network (e.g., swelling, degradation, and mechanical) to be tuned.

Original languageEnglish
Pages (from-to)5985-5992
Number of pages8
Issue number26
StatePublished - Dec 13 2011


  • Hydrogel
  • Poly(β-amino ester)
  • Swelling

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry


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