A sweet success for substrate engineering

Byron R. Griffith; Jon S. Thorson

doi:10.1038/nchembio1206-659

A sweet success for substrate engineering

Byron R. Griffith, Jon S. Thorson

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

Chemically synthesizing complex oligosaccharides remains a significant challenge. Through the addition of hydrophobic appendages to 'unnatural' substrates, some oligosaccharide-forming glycosyltransferases can direct the formation of distinct sugar linkages while maintaining stereoselectivity.

Original language	English
Pages (from-to)	659-660
Number of pages	2
Journal	Nature Chemical Biology
Volume	2
Issue number	12
DOIs	https://doi.org/10.1038/nchembio1206-659
State	Published - Dec 2006

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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title = "A sweet success for substrate engineering",

abstract = "Chemically synthesizing complex oligosaccharides remains a significant challenge. Through the addition of hydrophobic appendages to 'unnatural' substrates, some oligosaccharide-forming glycosyltransferases can direct the formation of distinct sugar linkages while maintaining stereoselectivity.",

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AU - Thorson, Jon S.

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JO - Nature Chemical Biology

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A sweet success for substrate engineering

Abstract

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