A Synthesis of N -Substituted β-Alanines: Michael Addition of Amines to Trimethylsilyl Acrylate

Stefan Kwiatkowski, Azhwarsamy Jeganathan, Thomas Tobin, David S. Watt

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The Michael addition of primary and secondary amines 2 to tromethylsilyl acrylate (1) afforded β-(alkylamino)- and β-(dialkylamino)-propionic acids 4, respectively, in good yield.

Original languageEnglish
Pages (from-to)946-949
Number of pages4
JournalSynthesis
Volume1989
Issue number12
DOIs
StatePublished - 1989

Bibliographical note

Publisher Copyright:
© 1989 Georg Thieme Verlag. All rights reserved.

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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