A text messaging intervention to promote medication adherence for patients with coronary heart disease: A randomized controlled trial

Linda G. Park; Jill Howie-Esquivel; Misook L. Chung; Kathleen Dracup

doi:10.1016/j.pec.2013.10.027

A text messaging intervention to promote medication adherence for patients with coronary heart disease: A randomized controlled trial

Linda G. Park, Jill Howie-Esquivel, Misook L. Chung, Kathleen Dracup

College of Nursing

Research output: Contribution to journal › Article › peer-review

149 Scopus citations

Abstract

Objective: Pharmacologic treatment for secondary prevention of coronary heart disease (CHD) is critical to prevent adverse clinical outcomes. In a randomized controlled trial, we compared antiplatelet and statin adherence among patients with CHD who received: (1) text messages (TM) for medication reminders and education, (2) educational TM only, or (3) No TM. Methods: A mobile health intervention delivered customized TM for 30 days. We assessed and analyzed medication adherence with electronic monitoring devices [Medication Event Monitoring System (MEMS)] by one-way ANOVA and Welch tests, two-way TM response rates by t-tests, and self-reported adherence (Morisky Medication Adherence Scale) by Repeated Measures ANOVA. Results: Among 90 patients (76% male, mean age 59.2 years), MEMS revealed patients who received TM for antiplatelets had a higher percentage of correct doses taken ( p= 0.02), percentage number of doses taken ( p= 0.01), and percentage of prescribed doses taken on schedule ( p= 0.01). TM response rates were higher for antiplatelets than statins ( p= 0.005). Self-reported adherence revealed no significant differences among groups. Conclusion: TM increased adherence to antiplatelet therapy demonstrated by MEMS and TM responses. Practice implications: Feasibility and high satisfaction were established. Mobile health interventions show promise in promoting medication adherence.

Original language	English
Pages (from-to)	261-268
Number of pages	8
Journal	Patient Education and Counseling
Volume	94
Issue number	2
DOIs	https://doi.org/10.1016/j.pec.2013.10.027
State	Published - Feb 2014

Bibliographical note

Funding Information:
Funding for research materials was provided by a grant from the Graduate Division of University of California, San Francisco and a scholarship from the UCSF/Hartford Center of Geriatric Nursing Excellence. CareSpeak Communications provided the use of the mobile Health manager platform, which is designed to improve medical therapy adherence using two-way text messaging.

Keywords

Antiplatelets
Coronary heart disease
Medication adherence
Mobile phone
Statins
Text messaging

ASJC Scopus subject areas

Medicine (all)

Access to Document

10.1016/j.pec.2013.10.027

Cite this

@article{9eaabee9a56340daa76747689efd8f5f,

title = "A text messaging intervention to promote medication adherence for patients with coronary heart disease: A randomized controlled trial",

abstract = "Objective: Pharmacologic treatment for secondary prevention of coronary heart disease (CHD) is critical to prevent adverse clinical outcomes. In a randomized controlled trial, we compared antiplatelet and statin adherence among patients with CHD who received: (1) text messages (TM) for medication reminders and education, (2) educational TM only, or (3) No TM. Methods: A mobile health intervention delivered customized TM for 30 days. We assessed and analyzed medication adherence with electronic monitoring devices [Medication Event Monitoring System (MEMS)] by one-way ANOVA and Welch tests, two-way TM response rates by t-tests, and self-reported adherence (Morisky Medication Adherence Scale) by Repeated Measures ANOVA. Results: Among 90 patients (76% male, mean age 59.2 years), MEMS revealed patients who received TM for antiplatelets had a higher percentage of correct doses taken ( p= 0.02), percentage number of doses taken ( p= 0.01), and percentage of prescribed doses taken on schedule ( p= 0.01). TM response rates were higher for antiplatelets than statins ( p= 0.005). Self-reported adherence revealed no significant differences among groups. Conclusion: TM increased adherence to antiplatelet therapy demonstrated by MEMS and TM responses. Practice implications: Feasibility and high satisfaction were established. Mobile health interventions show promise in promoting medication adherence.",

keywords = "Antiplatelets, Coronary heart disease, Medication adherence, Mobile phone, Statins, Text messaging",

author = "Park, {Linda G.} and Jill Howie-Esquivel and Chung, {Misook L.} and Kathleen Dracup",

note = "Funding Information: Funding for research materials was provided by a grant from the Graduate Division of University of California, San Francisco and a scholarship from the UCSF/Hartford Center of Geriatric Nursing Excellence. CareSpeak Communications provided the use of the mobile Health manager platform, which is designed to improve medical therapy adherence using two-way text messaging. ",

year = "2014",

month = feb,

doi = "10.1016/j.pec.2013.10.027",

language = "English",

volume = "94",

pages = "261--268",

number = "2",

}

TY - JOUR

T1 - A text messaging intervention to promote medication adherence for patients with coronary heart disease

T2 - A randomized controlled trial

AU - Park, Linda G.

AU - Howie-Esquivel, Jill

AU - Chung, Misook L.

AU - Dracup, Kathleen

N1 - Funding Information: Funding for research materials was provided by a grant from the Graduate Division of University of California, San Francisco and a scholarship from the UCSF/Hartford Center of Geriatric Nursing Excellence. CareSpeak Communications provided the use of the mobile Health manager platform, which is designed to improve medical therapy adherence using two-way text messaging.

PY - 2014/2

Y1 - 2014/2

N2 - Objective: Pharmacologic treatment for secondary prevention of coronary heart disease (CHD) is critical to prevent adverse clinical outcomes. In a randomized controlled trial, we compared antiplatelet and statin adherence among patients with CHD who received: (1) text messages (TM) for medication reminders and education, (2) educational TM only, or (3) No TM. Methods: A mobile health intervention delivered customized TM for 30 days. We assessed and analyzed medication adherence with electronic monitoring devices [Medication Event Monitoring System (MEMS)] by one-way ANOVA and Welch tests, two-way TM response rates by t-tests, and self-reported adherence (Morisky Medication Adherence Scale) by Repeated Measures ANOVA. Results: Among 90 patients (76% male, mean age 59.2 years), MEMS revealed patients who received TM for antiplatelets had a higher percentage of correct doses taken ( p= 0.02), percentage number of doses taken ( p= 0.01), and percentage of prescribed doses taken on schedule ( p= 0.01). TM response rates were higher for antiplatelets than statins ( p= 0.005). Self-reported adherence revealed no significant differences among groups. Conclusion: TM increased adherence to antiplatelet therapy demonstrated by MEMS and TM responses. Practice implications: Feasibility and high satisfaction were established. Mobile health interventions show promise in promoting medication adherence.

AB - Objective: Pharmacologic treatment for secondary prevention of coronary heart disease (CHD) is critical to prevent adverse clinical outcomes. In a randomized controlled trial, we compared antiplatelet and statin adherence among patients with CHD who received: (1) text messages (TM) for medication reminders and education, (2) educational TM only, or (3) No TM. Methods: A mobile health intervention delivered customized TM for 30 days. We assessed and analyzed medication adherence with electronic monitoring devices [Medication Event Monitoring System (MEMS)] by one-way ANOVA and Welch tests, two-way TM response rates by t-tests, and self-reported adherence (Morisky Medication Adherence Scale) by Repeated Measures ANOVA. Results: Among 90 patients (76% male, mean age 59.2 years), MEMS revealed patients who received TM for antiplatelets had a higher percentage of correct doses taken ( p= 0.02), percentage number of doses taken ( p= 0.01), and percentage of prescribed doses taken on schedule ( p= 0.01). TM response rates were higher for antiplatelets than statins ( p= 0.005). Self-reported adherence revealed no significant differences among groups. Conclusion: TM increased adherence to antiplatelet therapy demonstrated by MEMS and TM responses. Practice implications: Feasibility and high satisfaction were established. Mobile health interventions show promise in promoting medication adherence.

KW - Antiplatelets

KW - Coronary heart disease

KW - Medication adherence

KW - Mobile phone

KW - Statins

KW - Text messaging

UR - http://www.scopus.com/inward/record.url?scp=84892782214&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84892782214&partnerID=8YFLogxK

U2 - 10.1016/j.pec.2013.10.027

DO - 10.1016/j.pec.2013.10.027

M3 - Article

C2 - 24321403

AN - SCOPUS:84892782214

SN - 0738-3991

VL - 94

SP - 261

EP - 268

JO - Patient Education and Counseling

JF - Patient Education and Counseling

IS - 2

ER -

A text messaging intervention to promote medication adherence for patients with coronary heart disease: A randomized controlled trial

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this