A working model for the type III secretion mechanism in Chlamydia

Joshua C. Ferrell, Kenneth A. Fields

Research output: Contribution to journalShort surveypeer-review

32 Scopus citations


It has been appreciated for almost 20 years that members of the Chlamydiales possess a virulence-associated type III secretion mechanism. Given the obligate intracellular nature of these bacteria, defining exactly how type III secretion functions to promote pathogenesis has been challenging. We present a working model herein that is based on current evidence.

Original languageEnglish
Pages (from-to)84-92
Number of pages9
JournalMicrobes and Infection
Issue number2
StatePublished - Feb 1 2016

Bibliographical note

Publisher Copyright:
© 2015 Institut Pasteur.


  • Effector
  • Pathogenesis
  • Secretion

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases


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