Abstract
It has been appreciated for almost 20 years that members of the Chlamydiales possess a virulence-associated type III secretion mechanism. Given the obligate intracellular nature of these bacteria, defining exactly how type III secretion functions to promote pathogenesis has been challenging. We present a working model herein that is based on current evidence.
Original language | English |
---|---|
Pages (from-to) | 84-92 |
Number of pages | 9 |
Journal | Microbes and Infection |
Volume | 18 |
Issue number | 2 |
DOIs | |
State | Published - Feb 1 2016 |
Bibliographical note
Funding Information:KAF is supported by a Public Health Service grant from the National Institutes of Health , NIAID ( AI0065530 ).
Publisher Copyright:
© 2015 Institut Pasteur.
Keywords
- Effector
- Pathogenesis
- Secretion
ASJC Scopus subject areas
- Microbiology
- Immunology
- Infectious Diseases