A working model for the type III secretion mechanism in Chlamydia

Joshua C. Ferrell; Kenneth A. Fields

doi:10.1016/j.micinf.2015.10.006

A working model for the type III secretion mechanism in Chlamydia

Joshua C. Ferrell, Kenneth A. Fields

Microbiology, Immunology, and Molecular Genetics

Research output: Contribution to journal › Short survey › peer-review

29 Scopus citations

Abstract

It has been appreciated for almost 20 years that members of the Chlamydiales possess a virulence-associated type III secretion mechanism. Given the obligate intracellular nature of these bacteria, defining exactly how type III secretion functions to promote pathogenesis has been challenging. We present a working model herein that is based on current evidence.

Original language	English
Pages (from-to)	84-92
Number of pages	9
Journal	Microbes and Infection
Volume	18
Issue number	2
DOIs	https://doi.org/10.1016/j.micinf.2015.10.006
State	Published - Feb 1 2016

Bibliographical note

Funding Information:
KAF is supported by a Public Health Service grant from the National Institutes of Health , NIAID ( AI0065530 ).

Publisher Copyright:
© 2015 Institut Pasteur.

Keywords

Effector
Pathogenesis
Secretion

ASJC Scopus subject areas

Microbiology
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.micinf.2015.10.006

Cite this

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title = "A working model for the type III secretion mechanism in Chlamydia",

abstract = "It has been appreciated for almost 20 years that members of the Chlamydiales possess a virulence-associated type III secretion mechanism. Given the obligate intracellular nature of these bacteria, defining exactly how type III secretion functions to promote pathogenesis has been challenging. We present a working model herein that is based on current evidence.",

keywords = "Effector, Pathogenesis, Secretion",

author = "Ferrell, {Joshua C.} and Fields, {Kenneth A.}",

note = "Funding Information: KAF is supported by a Public Health Service grant from the National Institutes of Health , NIAID ( AI0065530 ). Publisher Copyright: {\textcopyright} 2015 Institut Pasteur.",

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doi = "10.1016/j.micinf.2015.10.006",

language = "English",

volume = "18",

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T1 - A working model for the type III secretion mechanism in Chlamydia

AU - Ferrell, Joshua C.

AU - Fields, Kenneth A.

PY - 2016/2/1

Y1 - 2016/2/1

N2 - It has been appreciated for almost 20 years that members of the Chlamydiales possess a virulence-associated type III secretion mechanism. Given the obligate intracellular nature of these bacteria, defining exactly how type III secretion functions to promote pathogenesis has been challenging. We present a working model herein that is based on current evidence.

AB - It has been appreciated for almost 20 years that members of the Chlamydiales possess a virulence-associated type III secretion mechanism. Given the obligate intracellular nature of these bacteria, defining exactly how type III secretion functions to promote pathogenesis has been challenging. We present a working model herein that is based on current evidence.

KW - Effector

KW - Pathogenesis

KW - Secretion

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UR - http://www.scopus.com/inward/citedby.url?scp=84957843455&partnerID=8YFLogxK

U2 - 10.1016/j.micinf.2015.10.006

DO - 10.1016/j.micinf.2015.10.006

M3 - Short survey

C2 - 26515030

AN - SCOPUS:84957843455

SN - 1286-4579

VL - 18

SP - 84

EP - 92

JO - Microbes and Infection

JF - Microbes and Infection

IS - 2

ER -

A working model for the type III secretion mechanism in Chlamydia

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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