A system is presented that may simplify the study of accessory cell reuirements for CTL generation. Cortisone resistant (CR) thymocytes containing alloreactive CTL precursors do not respond to allogeneic tumor cells unless non-T accessory cells are added to culture. In addition, splenic T cells do not respond to allogeneic tumor cells in the absence of non-T accessory cells. These accessory cells share several properties of macrophages.
|Number of pages||7|
|Journal||Journal of Immunology|
|State||Published - 1979|
ASJC Scopus subject areas
- Immunology and Allergy