Accessory cell requirements for the generation of cytolytic T lymphocytes

C. T. Lutz, F. W. Fitch

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

A system is presented that may simplify the study of accessory cell reuirements for CTL generation. Cortisone resistant (CR) thymocytes containing alloreactive CTL precursors do not respond to allogeneic tumor cells unless non-T accessory cells are added to culture. In addition, splenic T cells do not respond to allogeneic tumor cells in the absence of non-T accessory cells. These accessory cells share several properties of macrophages.

Original languageEnglish
Pages (from-to)2598-2604
Number of pages7
JournalJournal of Immunology
Volume122
Issue number6
StatePublished - 1979

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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