TY - JOUR
T1 - Actigraphy-based sleep characteristics and aortic stiffness
T2 - the Multi-Ethnic Study of Atherosclerosis
AU - Logan, Jeongok G.
AU - Kang, Hyojung
AU - Lobo, Jennifer Mason
AU - Sohn, Min Woong
AU - Lin, Gen Min
AU - Lima, Joao A.C.
AU - Punjabi, Naresh M.
AU - Redline, Susan
AU - Kwon, Younghoon
N1 - Publisher Copyright:
© 2018 American Heart Association
PY - 2018/12
Y1 - 2018/12
N2 - The study aimed to examine the association between objective estimates of sleep duration and quality and aortic stiffness while accounting for the potential confounding effect of sleep-disordered breathing. Participants were part of the Multi-Ethnic Study of Atherosclerosis Sleep study. Sleep duration and quality were assessed by 7-day wrist actigraphy, sleep-disordered breathing by home polysomnography, and aortic stiffness by magnetic resonance imaging–based aortic pulse wave velocity (aPWV), ascending and descending aorta distensibility. Aortic stiffness of participants with “normal” sleep duration (6-8 hours) were compared with those of “short” (<6 hours) and “long” sleep duration (>8 hours) adjusting for common cardiovascular risk factors and apnea-hypopnea index. The sample consisted of 908 participants (mean age 68.4 ± 9.1 years, 55.3% female). There was a significant linear trend of increased aPWV across short (n = 252), normal (n = 552), and long sleep durations (n = 104) (P for trend = .008). Multivariable analysis showed that people with short sleep duration had 0.94 m/s lower aPWV (95% CI: −1.54, −0.35), compared with those with normal sleep duration. In this ethnically diverse community cohort, habitual short sleep duration as estimated by actigraphy was associated with lower aortic stiffness.
AB - The study aimed to examine the association between objective estimates of sleep duration and quality and aortic stiffness while accounting for the potential confounding effect of sleep-disordered breathing. Participants were part of the Multi-Ethnic Study of Atherosclerosis Sleep study. Sleep duration and quality were assessed by 7-day wrist actigraphy, sleep-disordered breathing by home polysomnography, and aortic stiffness by magnetic resonance imaging–based aortic pulse wave velocity (aPWV), ascending and descending aorta distensibility. Aortic stiffness of participants with “normal” sleep duration (6-8 hours) were compared with those of “short” (<6 hours) and “long” sleep duration (>8 hours) adjusting for common cardiovascular risk factors and apnea-hypopnea index. The sample consisted of 908 participants (mean age 68.4 ± 9.1 years, 55.3% female). There was a significant linear trend of increased aPWV across short (n = 252), normal (n = 552), and long sleep durations (n = 104) (P for trend = .008). Multivariable analysis showed that people with short sleep duration had 0.94 m/s lower aPWV (95% CI: −1.54, −0.35), compared with those with normal sleep duration. In this ethnically diverse community cohort, habitual short sleep duration as estimated by actigraphy was associated with lower aortic stiffness.
KW - Arterial stiffness
KW - pulse wave velocity
KW - sleep duration
KW - sleep quality
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U2 - 10.1016/j.jash.2018.09.008
DO - 10.1016/j.jash.2018.09.008
M3 - Article
C2 - 30396853
AN - SCOPUS:85055915577
SN - 1933-1711
VL - 12
SP - 841
EP - 849
JO - Journal of the American Society of Hypertension
JF - Journal of the American Society of Hypertension
IS - 12
ER -