Abstract
Probing the unknown: The immunoproteasome, an alternative form of the constitutive proteasome, has been implicated in a number of pathological states such as cancer and autoimmune diseases. In an effort to understand the role of the immunoproteasome in cells, the first immunoproteasome-specific near-infrared fluorescent probe has been developed.
| Original language | English |
|---|---|
| Pages (from-to) | 1899-1903 |
| Number of pages | 5 |
| Journal | ChemBioChem |
| Volume | 13 |
| Issue number | 13 |
| DOIs | |
| State | Published - Sep 3 2012 |
Funding
| Funders | Funder number |
|---|---|
| National Childhood Cancer Registry – National Cancer Institute | R01CA128903 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Activity-based probes
- Immunoproteasome
- Near-infrared fluorescent probes
- Proteomics
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Organic Chemistry
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