Acute effects of alcohol on inhibitory control and information processing in high and low sensation-seekers

Mark T. Fillmore; Erik W. Ostling; Catherine A. Martin; Thomas H. Kelly

doi:10.1016/j.drugalcdep.2008.09.007

Acute effects of alcohol on inhibitory control and information processing in high and low sensation-seekers

Mark T. Fillmore, Erik W. Ostling, Catherine A. Martin, Thomas H. Kelly

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

Abstract

Sensation-seeking is a personality characteristic that has been associated with drug abuse. Some evidence suggests that sensation-seekers might experience increased rewarding effects from drugs of abuse, possibly contributing to the association between sensation-seeking and risk for drug abuse. The present study examined the effects of three doses of alcohol (0.0 g/kg, 0.45 g/kg, and 0.65 g/kg) on inhibitory control, information processing, and subjective ratings in a group of high sensation-seekers and a group of low sensation-seekers (N = 20). Inhibitory control was measured by a cued go/no-go task and speed of information processing was assessed by the Rapid Information Processing (RIP) task. Alcohol impaired inhibitory control and information processing. Group differences were also observed. Compared with their low sensation-seeking counterparts, high sensation-seekers demonstrated increased sensitivity to the subjective rewarding effects of alcohol and a poorer degree of inhibitory control that was further impaired by alcohol. The findings highlight reward- and cognitive-based mechanisms by which sensation-seeking could operate to increase risk for alcohol abuse.

Original language	English
Pages (from-to)	91-99
Number of pages	9
Journal	Drug and Alcohol Dependence
Volume	100
Issue number	1-2
DOIs	https://doi.org/10.1016/j.drugalcdep.2008.09.007
State	Published - Feb 1 2009

Bibliographical note

Funding Information:
The project described was supported by Award Number P50 DA 05312, P20 RR 15592, R01 AA12895, and R21 DA021027 from the National Institute On Alcohol Abuse And Alcoholism. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute On Alcohol Abuse And Alcoholism or the National Institutes of Health. These institutes had no further role in study design; in the collection, analysis and interpretation of data; in the writing of the report; or in the decision to submit the paper for publication.

Keywords

Alcohol
Information processing
Inhibitory control
Sensation-seeking

ASJC Scopus subject areas

Toxicology
Pharmacology
Psychiatry and Mental health
Pharmacology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.drugalcdep.2008.09.007

Cite this

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title = "Acute effects of alcohol on inhibitory control and information processing in high and low sensation-seekers",

abstract = "Sensation-seeking is a personality characteristic that has been associated with drug abuse. Some evidence suggests that sensation-seekers might experience increased rewarding effects from drugs of abuse, possibly contributing to the association between sensation-seeking and risk for drug abuse. The present study examined the effects of three doses of alcohol (0.0 g/kg, 0.45 g/kg, and 0.65 g/kg) on inhibitory control, information processing, and subjective ratings in a group of high sensation-seekers and a group of low sensation-seekers (N = 20). Inhibitory control was measured by a cued go/no-go task and speed of information processing was assessed by the Rapid Information Processing (RIP) task. Alcohol impaired inhibitory control and information processing. Group differences were also observed. Compared with their low sensation-seeking counterparts, high sensation-seekers demonstrated increased sensitivity to the subjective rewarding effects of alcohol and a poorer degree of inhibitory control that was further impaired by alcohol. The findings highlight reward- and cognitive-based mechanisms by which sensation-seeking could operate to increase risk for alcohol abuse.",

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note = "Funding Information: The project described was supported by Award Number P50 DA 05312, P20 RR 15592, R01 AA12895, and R21 DA021027 from the National Institute On Alcohol Abuse And Alcoholism. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute On Alcohol Abuse And Alcoholism or the National Institutes of Health. These institutes had no further role in study design; in the collection, analysis and interpretation of data; in the writing of the report; or in the decision to submit the paper for publication. ",

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Acute effects of alcohol on inhibitory control and information processing in high and low sensation-seekers

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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