Acute phase response in bronchiectasis and bronchus carcinoma1

A. E. Nel, A. F. Strachan, H. E. Welke, F. C. De Beer

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Measurement of the acute phase response in patients suffering from bronchiectasis, emphysema, bronchus carcinoma and various benign space-occupying lesions was undertaken, using sensitive immunoradiometric assays for C-reactive protein (CRP) and serum amyloid-A protein (SAA). In some patients with bronchiectasis, clinically judged to be in remission, the results show a major ongoing acute phase response. Such a response could predispose these patients to the development of reactive secondary amyloidosis. In bronchus carcinoma the application of these measurements to judge the extent of tumor growth is limited as infection-complicating obstruction is a more potent initiator of the acute phase response than the neoplastic process per se.

Original languageEnglish
Pages (from-to)196-200
Number of pages5
Issue number3
StatePublished - 1985


  • Acute phase
  • Bronchiectasis
  • Bronchus carcinoma
  • C-reactive protein
  • Serum amyloid A protein

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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