Abstract
Daptomycin is an antibiotic that is being used with increasing frequency for the treatment of methicillin resistant Staphylococcus aureus (MRSA) infections. We report a 65-year-old male patient with vertebral osteomyelitis due to MRSA who developed acute respiratory failure secondary to eosinophilic pneumonia after starting daptomycin therapy. Bronchoscopy showed a bronchoalveolar lavage (BAL) with 33% eosinophilia and the transbronchial biopsies revealed organizing pneumonia with many eosinophils. The patient responded rapidly to drug cessation and steroid therapy. Eosinophilic pneumonia is a rare but potentially serious complication of daptomycin therapy that, if recognized early, responds quickly to drug cessation and steroid therapy.
Original language | English |
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Pages (from-to) | 235-237 |
Number of pages | 3 |
Journal | Respiratory Medicine CME |
Volume | 1 |
Issue number | 3 |
DOIs | |
State | Published - 2008 |
Keywords
- Acute respiratory failure
- Antibiotic
- Drug induced
- Eosinophilic lung disease
- Eosinophilic pneumonia
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine