TY - JOUR
T1 - Acyl CoA binding proteins are required for cuticle formation and plant responses to microbes
AU - Xia, Ye
AU - Yu, Keshun
AU - Gao, Qing Ming
AU - Wilson, Ella V.
AU - Navarre, Duroy
AU - Kachroo, Pradeep
AU - Kachroo, Aardra
PY - 2012/10/8
Y1 - 2012/10/8
N2 - Fatty acids (FA) and lipids are well known regulators of plant defense. Our previous studies have shown that components of prokaryotic (plastidal) FA biosynthesis pathway regulate various aspects of plant defense. Here, we investigated the defense related roles of the soluble acyl CoA binding proteins (ACBPs), which are thought to facilitate the intracellular transport of FA/lipids. We show that ACBP3 and 4 are required for maintaining normal lipid levels and that ACBP3 contributes to the lipid flux between the prokaryotic and eukaryotic pathways. We also show that loss of ACBP3, 4, or 6 impair normal development of the cuticle and affect both basal and resistance protein-mediated defense against bacterial and fungal pathogens. Loss of ACBP3, 4, or 6 also inhibits the induction of systemic acquired resistance (SAR) due to the plants inability to generate SAR inducing signal(s). Together, these data show that ACBP3, ACBP4, and ACBP6 are required for cuticle development as well as defense against microbial pathogens.
AB - Fatty acids (FA) and lipids are well known regulators of plant defense. Our previous studies have shown that components of prokaryotic (plastidal) FA biosynthesis pathway regulate various aspects of plant defense. Here, we investigated the defense related roles of the soluble acyl CoA binding proteins (ACBPs), which are thought to facilitate the intracellular transport of FA/lipids. We show that ACBP3 and 4 are required for maintaining normal lipid levels and that ACBP3 contributes to the lipid flux between the prokaryotic and eukaryotic pathways. We also show that loss of ACBP3, 4, or 6 impair normal development of the cuticle and affect both basal and resistance protein-mediated defense against bacterial and fungal pathogens. Loss of ACBP3, 4, or 6 also inhibits the induction of systemic acquired resistance (SAR) due to the plants inability to generate SAR inducing signal(s). Together, these data show that ACBP3, ACBP4, and ACBP6 are required for cuticle development as well as defense against microbial pathogens.
KW - Acyl CoA binding proteins
KW - Cuticle
KW - Fatty acids
KW - Plant defense
KW - Systemic acquired resistance
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U2 - 10.3389/fpls.2012.00224
DO - 10.3389/fpls.2012.00224
M3 - Article
AN - SCOPUS:84875601183
SN - 1664-462X
VL - 3
JO - Frontiers in Plant Science
JF - Frontiers in Plant Science
IS - OCT
M1 - 224
ER -