Adaptive changes in membrane lipid composition and fluidity as the basis for ethanol tolerance

J. M. Littleton

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

This paper is intended as a brief commentary on the evidence for adaptation to ethanol at the level of the cell membrane with more detailed consideration of the possible mechanisms for such adaptation. Methodological and conceptual problems are raised and the current views of ethanol tolerance at the membrane level are criticised. The paper includes an abstract of work carried out by the author's group on changes in membrane phospholipid composition of mice during exposure to ethanol by inhalation.

Original languageEnglish
Pages (from-to)189-195
Number of pages7
JournalDrug and Alcohol Dependence
Volume4
Issue number1-2
DOIs
StatePublished - 1979

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology
  • Psychiatry and Mental health
  • Pharmacology (medical)

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