Adhesion properties of a neuronal epitope recognized by the monoclonal antibody HNK-1

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70 Scopus citations

Abstract

A carbohydrate epitope on adhesion proteins of the developing nervous system, and on myelin-associated glycoprotein, is recognized by the monoclonal antibody HNK-1. The HNK-1 epitope bearing proteins and the monoclonal antibody alter, in a dose-dependent manner, the interaction between neurons and neurite-promoting substrate-attached materials released from cultured neural cells.

Original languageEnglish
Pages (from-to)20-25
Number of pages6
JournalBrain Research
Volume367
Issue number1-2
DOIs
StatePublished - Mar 5 1986

Keywords

  • myelin-associated glycoprotein
  • neurite-promoting substrate-attached molecule
  • neuronal adhesion protein

ASJC Scopus subject areas

  • General Neuroscience
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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